Endocrine Abstracts

Introduction: Autoimmune polyglandular syndrome type 2 (APS2) is the most common form of the polyglandular failure syndromes. Seventy-five percent of cases occur in women. Adrenal insufficiency is the principal manifestation occurs with autoimmune thyroid disease or type I diabetes mellitus. The incidence of autoimmune thyroid diseases in APS2 is 70%; 30% Hashimoto’s thyroiditis, 20% non toxic goiter, 20% hypertyroidism is seen. We will discuss about a patient with APS2, ...

Aim: To compare macular pigment optical density (MPOD) in diabetic and non-diabetic patients by using heterochromatic flicker photometry and to investigate the correlation of MPOD with glycosylated hemoglobin (HbA1C), serum lipid levels and vitamin D levels.Methods: Sixty-seven patients with 10/0 visual acuity were divided into group 1 (controls, n: 35) and group 2 (diabetics without retinopathy, n: 32). MPOD was measured with a heteroc...

Introduction: Giant cell granulomatous hypophysitis is a rare chronic inflammatory disorder of the pituitary gland. It is generally presents with a clinic of sellar mass lesion with pituitary insufficiency. Histologically it is characterized by composites of histiocytes, plasma cells and giant cells with or without areas of necrosis. Tuberculosis is a very rare cause of secondary granulomatous hypophysitis. We report a case presented with hypopituitarism symptoms due to tuberc...

Objective: Radioiodine (RAI), surgical and anti-thyroid drug therapy are the main options to treat Graves’ disease (GD). The aim of this study was to investigate theurapeutic options, their efficacy and adverse reactions of prophilthiouracil (PTU) and methimazole (MMI).Design: A total of 650 patients with GD were evaluated retrospectively. Treatments, adverse reactions, clinical and laboratory results were recorded. After 18 months of primary medica...

Background: In the presence of specific symptoms and signs, Cushing’s syndrome (CS) may be easily recognised. On the other hand, in overweight and obese patients without typical features of CS, diagnosis may be omitted. Our aim was to evaluate the prevalence of CS among overweight and obese patients.Methods: We enrolled 264 overweight and obese patients who has not overt CS clinical features between January 2012 and December 2014 at Ankara Numune Ed...

Introduction: Ectopic thyroid tissue is the result of abnormal gland migration from the foramen caecum to its normal pretracheal position. An ectopic thyroid can be lingual (at the base of the tongue), sub-lingual (below the tongue), prelaryngeal (in front of the larynx), or can be found at other rare sites. The most frequent noncervical location for ectopic thyroid tissue is the thoracic cavity. Here we discuss about a rare case of mediastinal ectopic thyroid tissue presentin...

Introduction: Pregnant women with known hypothyroidism must have monthly follow up with thyroid function tests. Appropriate L-thyroxin replacement dose can be given due to trimester specific thyroid stimulating hormone (TSH) levels. We will discuss about a hyperthyroid pregnant woman who was taking L-thyroxin replacement before and during the first trimester of pregnancy for hypothyroidism.Case: A 24-year old woman came to o...

Introduction: Fine-needle aspiration (FNA) is a simple, the most cost-effective, less invasive and a commonly used diagnostic tool for evaluating thyroid nodules. Recent times a tech-nique called fine-needle sampling non-aspiration (FNNA) or fine-needle capillary thyroid biopsies (FNC) has been more preferred. This technique prevents the use of suction so there is no aspiration crush and there-fore nondiagnostic outcomes are reduced. The aim of this prospective study was to co...

Ectopic secretion of corticotropin(ACTH) by nonpituitary tumors accounts for 10–15% of ACTH dependent Cushing’s syndrome (CS). Generally it is difficult to localize the ACTH secreting tumor by conventional imaging methods because these tumors are often small in size. Here we present a case of ectopic ACTH syndrome diagnosed with octreotide scan.Case: A 26-year-old male patient presented with moon face, purplish striae, supraclavicular fat pads ...

Pituitary adenomas which co-secrete GH and TSH accounts for <0.2% of all adenomas of the pituitary. Symptoms of hypertyroidism are usually masked by clinical manifestations of acromegaly. Here, we have reported the result of the primary one year long medical therapy in a case who was diagnosed to have adenoma co-secreting GH and TSH.Case: Seventy-years-old female patient has admitted with the complaints of excessive sweating, enlargement of hands and...